Are there any other vitamin supplements that work well with PQQ?
As you are probably aware from reading PQQ, pyrroloquinoline quinone seems to act in promoting mitochondriogenesis and, in a broader context, by protecting neural tissue. Compounds that may promote mitochondriogenesis included resveratrol, quercetin, and hydroxytyrosol (found in olive oil). Other agents that promote [...]
What are the effects of pyrroloquinoline quinone on glutamate? And, can PQQ be used for neuroprotection?
Some of the earliest reports regarding the potential physiological functions of PQQ have involved studies focusing on PQQ and neural function and neuroprotection. In experimental animal models, the effects of pyrroloquinoline quinone on glutamate are mechanisms that protect the redox [...]
Mitochondria can produce damaging reactive oxygen species (ROS) as a by-product of normal function. Over time, ROS degrade mitochondrial DNA (mtDNA), interfering with cellular energy production. When a cell loses mitochondria, eventually apoptosis or cell death can occur. Most cell’s strategy for dealing with damage is to “recycle” or turnover mitochondria on a [...]
A telomere is a region of repetitive DNA at the end of a chromosome. Telomeres protect the ends of a given chromosome’s DNA from deterioration (although the shortening of chromosome telomeres normally occurs during chromosome replication). All cells that make up tissues undergo some degree of turnover (replication and apoptosis, i.e. programmed cell [...]
As pyrroloquinoline quinone gets more popular, it is interesting to hear what people are saying about this intriguing compound. If you would like to describe how PQQ has helped (or not helped) you, leave a comment below and we will add your thoughts to this pyrroloquinoline quinone testimonial page:
I recently started supplementing with PQQ and [...]
Quinones are derived from aromatic compounds, such as benzene and naphthalene. There are thousands of aromatic compounds. Although a thorough discussion of organic chemistry related to quinone structure and aromatic compounds is somewhat beyond the scope of this informational site about pyrroloquinoline quinone, it is important to appreciate some of the following quinone [...]
What is a reasonable PQQ dosage for an active adult?
This question has not been fully resolved and is complicated by the inability to measure all forms of PQQ (pyrroloquinoline quinone | methoxatin). However, it is possible to make several good inferences from current animal studies and data for the pyrroloquinoline quinone content that researchers have found [...]
Does it make sense to call pyrroloquinoline quinone, vitamin PQQ? To make the case for the physiological and biomedical importance of PQQ, it is also important to appreciate that many of pyrroloquinoline quinone’s biological functions are universal.
Pyrroloquinoline quinone acts as growth factor to both plant and certain strains of bacteria. PQQ is a trophic factor [...]
Control of mitochondrial oxygen utilization and respiratory control is central to all aspects of normal growth and development. In a broad setting, mitochondria are central to normal glucose, amino acid and fatty acid oxidation, reactive oxygen species (ROS), i.e., antioxidant modulation, and ATP production, particularly during exercise. The mechanisms for mitochondrial regulation involve changes in [...]
It can be confidently speculated that pyrroloquinoline quinone (PQQ) was present throughout the earliest phases of biological conception. This is because compounds with the properties of PQQ are present in stellar dust. Cometary grains are considered to be the precursors of organic materials in early life on the earth. It can also be [...]
